By A. N. Paruta, R. Piekos
One in every of 3 volumes which jointly conceal all suggested solubility information for a massive pharmaceutical type: the sulfonamides. a data of solubility information is beneficial in all pharmaceutical study. released solubility information for the identify compounds were compiled and significantly evaluated, leading to instructed solubility values which practicing scientists may well use with self belief. each one quantity contains structural formulae and molecular weight information for the compounds coated, comfortably grouped jointly
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Additional resources for 4–Aminobenzenesulfonamides. 6-Membered Heterocyclic Substituents and Miscellaneous Systems
Erg. Dermatol. Hyg. 1941, 1938, 24, 398. 36 COMPONENTS : (1) ORIGINAL Benzenesulfonamide, 4-amino-N-2pyridinyl(sulfapyridine); C1 H [144-83-2] 1 1 N 1 30 2S ; Krllger-Thiemer, E. Arch. (2) Phosphoric acid, disodium salt; N a 2H P 0 4; [7558-94-4] (3) Phosphoric acid, monopotassium salt; K H 2P 0 4; [7778-77-0] Water; H 20 ; [7732-18-5] (4) MEASUREMENTS: Dermatol. PREPARED BY: R. Piekos Temperature; pH VALUES: Composition of 1/15M phosphate Solubility buffer solutions N a 2H P 0 4 1833 1942, 90-116.
J. Lab. ; Clin. Med. 188-9. [7732-18-5] VARIABLES : PREPARED BY: Temperature EXPERIMENTAL Strakosch, Ε. I. 28, 1942, 144-83-2] H 20 ; MEASUREMENTS: C l a r k , W . ; (sulfapyridine); S; 11 11 3°2 (2) 4-amino-N-2- R. 95 Calculated by ter b a t h thermostat soin was then filtered by through a washed stick entire and for was 24 h . excess in a w a - The satd asbestos app w a s kept at the then detd by INFORMATION AND PURITY OF Neither was MATERIALS; source nor purity of sulfapyridine specified. C02"-free d i s t d w a t e r w a s used.
ESTIMATED ERROR: Nothing specified REFERENCES: 1. Bratton, A. C ; J. Pharmacol. Marshall, Ε. Κ. , Jr. 1939, 66, 4. 24 COMPONENTS : (1) (2) ORIGINAL MEASUREMENTS: Benzenesulfonamide, 4-amino-N-2- Durel, M. ; pyridinyl- Bull. Soo. 1941, 251-9. (sulfapyridine); C1 H 1 1 N 1 30 2S ; [144-83-2] Water; [7732-18-5] H 20 ; VARIABLES : Allinne, M. Med. Hop. Paris III PREPARED BY: One temperature: 37°C R. 8 χ 10~ 3 _3 mol dm , compiler ) . AUXILIARY INFORMATION METHOD /APPARATUS /PROCEDURE : SOURCE AND PURITY OF MATERIALS: A mixt of sulfapyridine and water was Source and purity of sulfapyridine were agitated for 24 hours at 37°C.
4–Aminobenzenesulfonamides. 6-Membered Heterocyclic Substituents and Miscellaneous Systems by A. N. Paruta, R. Piekos